Emulated Clinical Trials from Longitudinal Real-World Data Efficiently Identify Candidates for Neurological Disease Modification: Examples from Parkinson’s Disease

Real-world healthcare data hold the potential to identify therapeutic solutions for progressive diseases by efficiently pinpointing safe and efficacious repurposing drug candidates. This approach circumvents key early clinical development challenges, particularly relevant for neurological diseases,...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Laifenfeld, Daphna, Yanover, Chen, Ozery-Flato, Michal, Shaham, Oded, Rosen-Zvi, Michal, Lev, Nirit, Goldschmidt, Yaara, Grossman, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100658/
https://ncbi.nlm.nih.gov/pubmed/33967767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.631584
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