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Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair

Ovarian cancer (OC) is the deadliest gynecologic malignancy, which is mainly due to late-stage diagnosis and chemotherapy resistance. Therefore, new and more effective treatments are urgently needed. The in vitro effects of Panobinostat (LBH), a histone deacetylase inhibitor that exerts pleiotropic...

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Vydáno v:Neoplasia
Hlavní autoři: Ovejero-Sánchez, María, González-Sarmiento, Rogelio, Herrero, Ana Belén
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100353/
https://ncbi.nlm.nih.gov/pubmed/33930758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2021.04.003
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