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Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair

Ovarian cancer (OC) is the deadliest gynecologic malignancy, which is mainly due to late-stage diagnosis and chemotherapy resistance. Therefore, new and more effective treatments are urgently needed. The in vitro effects of Panobinostat (LBH), a histone deacetylase inhibitor that exerts pleiotropic...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Ovejero-Sánchez, María, González-Sarmiento, Rogelio, Herrero, Ana Belén
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100353/
https://ncbi.nlm.nih.gov/pubmed/33930758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2021.04.003
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