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Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis

Osteoarthritis (OA) is the most common chronic joint disease in the elderly population. Growing evidence indicates that a balance between autophagy and apoptosis in chondrocytes plays a key role in OA’s cartilage degradation. Thus, drugs targeting the balance between apoptosis and autophagy are pote...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Liu, Yuan, Xu, Shi, Zhang, Haijun, Qian, Kaoliang, Huang, Jiachen, Gu, Xianger, Li, Yan, Fan, Yi, Hu, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100296/
https://ncbi.nlm.nih.gov/pubmed/33953172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03726-4
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