Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology

Long pentraxin PTX3, a pattern recognition molecule involved in innate immune responses, is upregulated by pro-inflammatory stimuli, contributors to secondary damage in traumatic brain injury (TBI). We analyzed PTX3 involvement in mice subjected to controlled cortical impact, a clinically relevant T...

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Vydáno v:Sci Rep
Hlavní autoři: Oggioni, Marco, Mercurio, Domenico, Minuta, Denise, Fumagalli, Stefano, Popiolek-Barczyk, Katarzyna, Sironi, Marina, Ciechanowska, Agata, Ippati, Stefania, De Blasio, Daiana, Perego, Carlo, Mika, Joanna, Garlanda, Cecilia, De Simoni, Maria-Grazia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100171/
https://ncbi.nlm.nih.gov/pubmed/33953334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89032-7
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