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Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant

Long pentraxin 3 (PTX3) is a non-redundant component of the humoral arm of innate immunity. The present study was designed to investigate the interaction of PTX3 with Neisseria meningitidis. PTX3 bound acapsular meningococcus, Neisseria-derived outer membrane vesicles (OMV) and 3 selected meningococ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bottazzi, Barbara, Santini, Laura, Savino, Silvana, Giuliani, Marzia M., Dueñas Díez, Ana I., Mancuso, Giuseppe, Beninati, Concetta, Sironi, Marina, Valentino, Sonia, Deban, Livija, Garlanda, Cecilia, Teti, Giuseppe, Pizza, Mariagrazia, Rappuoli, Rino, Mantovani, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364741/
https://ncbi.nlm.nih.gov/pubmed/25786110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120807
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