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Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells

Tobacco smoking is the largest risk factor for developing chronic obstructive pulmonary disease (COPD), and is associated with hyperresponsiveness of airway smooth muscle (ASM). Chronic exposure to cigarette smoke (CS) leads to airway inflammation and remodelling. However, the direct effect of gaseo...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Lin, JinHeng, Taggart, Michael, Borthwick, Lee, Fisher, Andrew, Brodlie, Malcolm, Sassano, M. Flori, Tarran, Robert, Gray, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100124/
https://ncbi.nlm.nih.gov/pubmed/33953304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89051-4
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