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Cigarette Smoke Exposure Induces Retrograde Trafficking of CFTR to the Endoplasmic Reticulum

Chronic obstructive pulmonary disease (COPD), which is most commonly caused by cigarette smoke (CS) exposure, is the third leading cause of death worldwide. The cystic fibrosis transmembrane conductance regulator (CFTR) is an apical membrane anion channel that is widely expressed in epithelia throug...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marklew, Abigail J., Patel, Waseema, Moore, Patrick J., Tan, Chong D., Smith, Amanda J., Sassano, M. Flori, Gray, Michael A., Tarran, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754399/
https://ncbi.nlm.nih.gov/pubmed/31541117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49544-9
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