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The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization

The mammalian globin gene clusters provide a paradigm for studying the relationship between genome structure and function. As blood stem cells undergo lineage specification and differentiation to form red blood cells, the chromatin structure and expression of the α-globin cluster change. The gradual...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Genet Dev
Main Authors: Oudelaar, A Marieke, Beagrie, Robert A, Kassouf, Mira T, Higgs, Douglas R
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100094/
https://ncbi.nlm.nih.gov/pubmed/33221670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2020.10.003
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