Quantifying Positional Isomers (QPI) by Top-Down Mass Spectrometry

Proteomics has exposed a plethora of posttranslational modifications, but demonstrating functional relevance requires new approaches. Top-down proteomics of intact proteins has the potential to fully characterize protein modifications in terms of amount, site(s), and the order in which they are depo...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Brunner, Andrea M., Lössl, Philip, Geurink, Paul P., Ovaa, Huib, Albanese, P., Altelaar, A.F. Maarten, Heck, Albert J.R., Scheltema, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
Soggetti:
Technological Innovation and Resources
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099777/
https://ncbi.nlm.nih.gov/pubmed/33711480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcpro.2021.100070
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