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Top-Down Identification and Characterization of Biomolecules by Mass Spectrometry
The most widely used modern mass spectrometers face severe performance limitations with molecules larger than a few kDa. For far larger biomolecules, a common practice has been to break these up chemically or enzymatically into fragments that are sufficiently small for the instrumentation available....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538795/ https://ncbi.nlm.nih.gov/pubmed/18571936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2008.05.013 |
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