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Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue

A mass difference between the measured molecular weight of a protein and that of its DNA-predicted sequence indicates sequence errors and/or posttranslational modifications. In the top-down mass spectrometry approach, the measured molecular ion is dissociated, and these fragment masses are matched a...

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Detalhes bibliográficos
Main Authors: Sze, Siu Kwan, Ge, Ying, Oh, HanBin, McLafferty, Fred W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122269/
https://ncbi.nlm.nih.gov/pubmed/11842225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251691898
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