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Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue
A mass difference between the measured molecular weight of a protein and that of its DNA-predicted sequence indicates sequence errors and/or posttranslational modifications. In the top-down mass spectrometry approach, the measured molecular ion is dissociated, and these fragment masses are matched a...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122269/ https://ncbi.nlm.nih.gov/pubmed/11842225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251691898 |
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