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Impact of study design and statistical model in pharmacogenetic studies with gene‐treatment interaction
Gene‐treatment interactions, just like drug‐drug interactions, can have dramatic effects on a patient response and therefore influence the clinician decision at the patient’s bedside. Crossover designs, although they are known to decrease the number of subjects in drug‐interaction studies, are seldo...
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| Publicado no: | CPT Pharmacometrics Syst Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8099447/ https://ncbi.nlm.nih.gov/pubmed/33951752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12624 |
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