CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation

Microtubule (MT) nucleation is regulated by the γ-tubulin ring complex (γTuRC), conserved from yeast to humans. In Saccharomyces cerevisiae, γTuRC is composed of seven identical γ-tubulin small complex (γTuSC) sub-assemblies, which associate helically to template MT growth. γTuRC assembly provides a...

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Veröffentlicht in:eLife
Hauptverfasser: Brilot, Axel F, Lyon, Andrew S, Zelter, Alex, Viswanath, Shruthi, Maxwell, Alison, MacCoss, Michael J, Muller, Eric G, Sali, Andrej, Davis, Trisha N, Agard, David A
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099430/
https://ncbi.nlm.nih.gov/pubmed/33949948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65168
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