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The Structure of the γ-Tubulin Small Complex: Implications of Its Architecture and Flexibility for Microtubule Nucleation

The γ-tubulin small complex (γ-TuSC) is an evolutionarily conserved heterotetramer essential for microtubule nucleation. We have determined the structure of the Saccharomyces cerevisiae γ-TuSC at 25-Å resolution by electron microscopy. γ-TuSC is Y-shaped, with an elongated body connected to two arms...

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Autori principali: Kollman, Justin M., Zelter, Alex, Muller, Eric G.D., Fox, Bethany, Rice, Luke M., Davis, Trisha N., Agard, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174199/
https://ncbi.nlm.nih.gov/pubmed/17978090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-09-0879
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