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XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions

Microtubule nucleation is spatiotemporally regulated in cells by several known molecules, including the template γ-tubulin and the polymerase XMAP215. The role of XMAP215 in nucleation is under debate, specifically whether it acts independently as a polymerase or acts dependently with γ-tubulin. We...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: King, Brianna R., Moritz, Michelle, Kim, Haein, Agard, David A., Asbury, Charles L., Davis, Trisha N.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550701/
https://ncbi.nlm.nih.gov/pubmed/32726183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-02-0160
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