Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses

An effective vaccine for respiratory syncytial virus (RSV) is an unrealized public health goal. A single dose of the prefusion-stabilized fusion (F) glycoprotein subunit vaccine (DS-Cav1) substantially increases serum-neutralizing activity in healthy adults. We sought to determine whether DS-Cav1 va...

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Publicat a:Immunity
Autors principals: Mukhamedova, Maryam, Wrapp, Daniel, Shen, Chen-Hsiang, Gilman, Morgan S.A., Ruckwardt, Tracy J., Schramm, Chaim A., Ault, Larissa, Chang, Lauren, Derrien-Colemyn, Alexandrine, Lucas, Sarah A.M., Ransier, Amy, Darko, Samuel, Phung, Emily, Wang, Lingshu, Zhang, Yi, Rush, Scott A., Madan, Bharat, Stewart-Jones, Guillaume B.E., Costner, Pamela J., Holman, LaSonji A., Hickman, Somia P., Berkowitz, Nina M., Doria-Rose, Nicole A., Morabito, Kaitlyn M., DeKosky, Brandon J., Gaudinski, Martin R., Chen, Grace L., Crank, Michelle C., Misasi, John, Sullivan, Nancy J., Douek, Daniel C., Kwong, Peter D., Graham, Barney S., McLellan, Jason S., Mascola, John R.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099422/
https://ncbi.nlm.nih.gov/pubmed/33823129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.03.004
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