Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses

An effective vaccine for respiratory syncytial virus (RSV) is an unrealized public health goal. A single dose of the prefusion-stabilized fusion (F) glycoprotein subunit vaccine (DS-Cav1) substantially increases serum-neutralizing activity in healthy adults. We sought to determine whether DS-Cav1 va...

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Publicado no:Immunity
Main Authors: Mukhamedova, Maryam, Wrapp, Daniel, Shen, Chen-Hsiang, Gilman, Morgan S.A., Ruckwardt, Tracy J., Schramm, Chaim A., Ault, Larissa, Chang, Lauren, Derrien-Colemyn, Alexandrine, Lucas, Sarah A.M., Ransier, Amy, Darko, Samuel, Phung, Emily, Wang, Lingshu, Zhang, Yi, Rush, Scott A., Madan, Bharat, Stewart-Jones, Guillaume B.E., Costner, Pamela J., Holman, LaSonji A., Hickman, Somia P., Berkowitz, Nina M., Doria-Rose, Nicole A., Morabito, Kaitlyn M., DeKosky, Brandon J., Gaudinski, Martin R., Chen, Grace L., Crank, Michelle C., Misasi, John, Sullivan, Nancy J., Douek, Daniel C., Kwong, Peter D., Graham, Barney S., McLellan, Jason S., Mascola, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099422/
https://ncbi.nlm.nih.gov/pubmed/33823129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.03.004
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