Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses

An effective vaccine for respiratory syncytial virus (RSV) is an unrealized public health goal. A single dose of the prefusion-stabilized fusion (F) glycoprotein subunit vaccine (DS-Cav1) substantially increases serum-neutralizing activity in healthy adults. We sought to determine whether DS-Cav1 va...

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書誌詳細
出版年:Immunity
主要な著者: Mukhamedova, Maryam, Wrapp, Daniel, Shen, Chen-Hsiang, Gilman, Morgan S.A., Ruckwardt, Tracy J., Schramm, Chaim A., Ault, Larissa, Chang, Lauren, Derrien-Colemyn, Alexandrine, Lucas, Sarah A.M., Ransier, Amy, Darko, Samuel, Phung, Emily, Wang, Lingshu, Zhang, Yi, Rush, Scott A., Madan, Bharat, Stewart-Jones, Guillaume B.E., Costner, Pamela J., Holman, LaSonji A., Hickman, Somia P., Berkowitz, Nina M., Doria-Rose, Nicole A., Morabito, Kaitlyn M., DeKosky, Brandon J., Gaudinski, Martin R., Chen, Grace L., Crank, Michelle C., Misasi, John, Sullivan, Nancy J., Douek, Daniel C., Kwong, Peter D., Graham, Barney S., McLellan, Jason S., Mascola, John R.
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099422/
https://ncbi.nlm.nih.gov/pubmed/33823129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.03.004
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