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IL‐19 induced by IL‐13/IL‐17A in the nasal epithelium of patients with chronic rhinosinusitis upregulates MMP‐9 expression via ERK/NF‐κB signaling pathway

BACKGROUND: Tissue remodeling is a crucial characteristic of chronic rhinosinusitis (CRS). Imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) is crucial for the pathologic tissue remodeling in CRS. Elevation of interleukin (IL)‐19 or MMP‐9 levels i...

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書目詳細資料
發表在:Clin Transl Allergy
Main Authors: Li, Xia, Huang, Jiancong, Chen, Xiaohong, Lai, Xiaoping, Huang, Zizhen, Li, Yue, Li, Shuaixiang, Chang, Lihong, Zhang, Gehua
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099262/
https://ncbi.nlm.nih.gov/pubmed/33900049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clt2.12003
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