Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis

Chronic rhinosinusitis (CRS) is a common chronic inflammatory disease of the upper airways involving nasal cavity and sinus. Deriving both from its clinical complexity with protean clinical manifestations as well its pathogenetic heterogeneity, the molecular mechanisms contributing to the pathogenes...

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Autores principales: Xiaohong Chen, Lihong Chang, Xia Li, Jiancong Huang, Luoying Yang, Xiaoping Lai, Zizhen Huang, Zhiyuan Wang, Xifu Wu, Jun Zhao, Joseph A. Bellanti, Song Guo Zheng, Gehua Zhang
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018-09-01
Colección:Frontiers in Immunology
Materias:
chronic rhinosinusitis
IL-17A
Tc cells
nasal epithelial cells
MMP-9
NF-κB
Acceso en línea:https://www.frontiersin.org/article/10.3389/fimmu.2018.02121/full
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