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Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10
Insulin controls glucose uptake into muscle and fat cells by inducing a net redistribution of glucose transporter 4 (GLUT4) from intracellular storage to the plasma membrane (PM). The TBC1D4-RAB10 signaling module is required for insulin-stimulated GLUT4 translocation to the PM, although where it in...
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| Publié dans: | Mol Biol Cell |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8098823/ https://ncbi.nlm.nih.gov/pubmed/33175605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-06-0356 |
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