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p53 and Brain Tumors: From Gene Mutations to Gene Therapy

The p53 tumor suppressor gene (TP53) is the most frequently altered gene in human cancer and is also found mutated in several types of brain tumors. Loss of p53 function plays a central role in the development of cancer. The characterization of the biochemical pathways by which p53 alteration trigge...

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Библиографические подробности
Опубликовано в: :Brain Pathol
Главные авторы: Fulci, Giulia, Ishii, Nobuaki, Van Meir, Erwin G.
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098259/
https://ncbi.nlm.nih.gov/pubmed/9804370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1998.tb00187.x
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