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p53 and Brain Tumors: From Gene Mutations to Gene Therapy

The p53 tumor suppressor gene (TP53) is the most frequently altered gene in human cancer and is also found mutated in several types of brain tumors. Loss of p53 function plays a central role in the development of cancer. The characterization of the biochemical pathways by which p53 alteration trigge...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Fulci, Giulia, Ishii, Nobuaki, Van Meir, Erwin G.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098259/
https://ncbi.nlm.nih.gov/pubmed/9804370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1998.tb00187.x
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