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JAK1 selective inhibitors for the treatment of spondyloarthropathies

As our understanding of the pathogenesis of SpA improves, focus has turned to the role janus kinase (JAK)-mediated signal transduction and inhibiting its actions as a therapeutic mechanism. Small molecule inhibitors of JAK exist, with variable selectivity for the different JAK isoforms. Less selecti...

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Detalhes bibliográficos
Publicado no:Rheumatology (Oxford)
Main Authors: White, Jonathan P E, Coates, Laura C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098108/
https://ncbi.nlm.nih.gov/pubmed/33950224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keaa815
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