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JAK1 selective inhibitors for the treatment of spondyloarthropathies

As our understanding of the pathogenesis of SpA improves, focus has turned to the role janus kinase (JAK)-mediated signal transduction and inhibiting its actions as a therapeutic mechanism. Small molecule inhibitors of JAK exist, with variable selectivity for the different JAK isoforms. Less selecti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Rheumatology (Oxford)
Hauptverfasser: White, Jonathan P E, Coates, Laura C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098108/
https://ncbi.nlm.nih.gov/pubmed/33950224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keaa815
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