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Early phase studies of JAK1 selective inhibitors in rheumatoid arthritis

The first approved Janus kinase (JAK) inhibitors for treatment of RA targeted more than one JAK molecule. Although this brings an advantage of simultaneous blocking of more cytokines involved in RA, it may also carry an increased risk of toxicity. Subsequently, more selective JAK inhibitors were dev...

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Détails bibliographiques
Publié dans:Rheumatology (Oxford)
Auteurs principaux: Avci, Ali Berkant, Feist, Eugen, Burmester, Gerd Rüdiger
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098113/
https://ncbi.nlm.nih.gov/pubmed/33950228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keaa893
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