The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells

The only currently available approach to early efficacy testing of tuberculosis (TB) vaccine candidates is in vivo preclinical challenge models. These typically include mice, guinea pigs and non-human primates (NHPs), which must be exposed to virulent M.tb in a ‘challenge’ experiment following vacci...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Tanner, Rachel, Hoogkamer, Emily, Bitencourt, Julia, White, Andrew, Boot, Charelle, Sombroek, Claudia C., Harris, Stephanie A., O'Shea, Matthew K., Wright, Daniel, Wittenberg, Rachel, Sarfas, Charlotte, Satti, Iman, Verreck, Frank A.W., Sharpe, Sally A., Fletcher, Helen A., McShane, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2021
Assuntos:
Method Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097740/
https://ncbi.nlm.nih.gov/pubmed/33976866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.51640.2
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