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The TrkA agonist gambogic amide augments skeletal adaptation to mechanical loading

The periosteal and endosteal surfaces of mature bone are densely innervated by sensory nerves expressing TrkA, the high-affinity receptor for nerve growth factor (NGF). In previous work, we demonstrated that administration of exogenous NGF significantly increased load-induced bone formation through...

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Dettagli Bibliografici
Pubblicato in:Bone
Autori principali: Fioravanti, Gabriella, Hua, Phuong Q., Tomlinson, Ryan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097708/
https://ncbi.nlm.nih.gov/pubmed/33713848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2021.115908
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