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Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome
X chromosome inactivation (XCI) is a dosage compensation mechanism in female mammals whereby transcription from one X chromosome is repressed. Analysis of human induced pluripotent stem cells (iPSCs) derived from female donors identified that low levels of XIST RNA correlated strongly with erosion o...
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| Опубликовано в: : | Cell Rep |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cell Press
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8097692/ https://ncbi.nlm.nih.gov/pubmed/33910018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109032 |
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