Activity of Clofazimine and TBI-166 against Mycobacterium tuberculosis in Different Administration Intervals in Mouse Tuberculosis Models

Clofazimine (CLO) and TBI-166 belong to the riminophenazine class of antimicrobial agent. TBI-166 exhibited promising antituberculosis activity in vitro and in animal models and is currently under phase I clinical development for the treatment of tuberculosis in China. To identify an optimal dosing...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Zhu, Hui, Fu, Lei, Wang, Bin, Chen, Xi, Zhao, Jiaojie, Huang, Haihong, Lu, Yu
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2021
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097486/
https://ncbi.nlm.nih.gov/pubmed/33431417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02164-20
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