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Population Pharmacokinetic and Pharmacodynamic Target Attainment Analysis of Cefazolin in the Serum and Hip Joint Capsule of Patients Undergoing Total Hip Arthroplasty

The objectives of this study were to evaluate the population pharmacokinetics of prophylactic cefazolin (CFZ) from its serum and hip joint capsule concentrations in patients undergoing total hip arthroplasty and to establish the pharmacodynamic target concentration exceeding the MIC for designing an...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Komatsu, Toshiaki, Natsume, Yui, Uchiyama, Katsufumi, Ikeda, Shinsuke, Tomoda, Yoshinori, Takayama, Yoko, Takaso, Masashi, Hanaki, Hideaki, Atsuda, Koichiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097485/
https://ncbi.nlm.nih.gov/pubmed/33526489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02114-20
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