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Population Pharmacokinetic and Pharmacodynamic Target Attainment Analysis of Cefazolin in the Serum and Hip Joint Capsule of Patients Undergoing Total Hip Arthroplasty

The objectives of this study were to evaluate the population pharmacokinetics of prophylactic cefazolin (CFZ) from its serum and hip joint capsule concentrations in patients undergoing total hip arthroplasty and to establish the pharmacodynamic target concentration exceeding the MIC for designing an...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Komatsu, Toshiaki, Natsume, Yui, Uchiyama, Katsufumi, Ikeda, Shinsuke, Tomoda, Yoshinori, Takayama, Yoko, Takaso, Masashi, Hanaki, Hideaki, Atsuda, Koichiro
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097485/
https://ncbi.nlm.nih.gov/pubmed/33526489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02114-20
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