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The Pup-Proteasome System Protects Mycobacteria from Antimicrobial Antifolates
Protein turnover via the Pup-proteasome system (PPS) is essential for nitric oxide resistance and virulence of Mycobacterium tuberculosis, the causative agent of tuberculosis. Our study revealed components of PPS as novel determinants of intrinsic antifolate resistance in both M. tuberculosis and no...
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| Gepubliceerd in: | Antimicrob Agents Chemother |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8097441/ https://ncbi.nlm.nih.gov/pubmed/33468462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01967-20 |
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