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The Pup-Proteasome System Protects Mycobacteria from Antimicrobial Antifolates
Protein turnover via the Pup-proteasome system (PPS) is essential for nitric oxide resistance and virulence of Mycobacterium tuberculosis, the causative agent of tuberculosis. Our study revealed components of PPS as novel determinants of intrinsic antifolate resistance in both M. tuberculosis and no...
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| Publicado no: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8097441/ https://ncbi.nlm.nih.gov/pubmed/33468462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01967-20 |
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