In Vitro and In Vivo Antibacterial Activities of a Novel Quinolone Compound, OPS-2071, against Clostridioides difficile

OPS-2071 is a novel quinolone antibacterial agent characterized by low oral absorption that reduces the risk of adverse events typical of fluoroquinolone class antibiotics. The in vitro and in vivo antibacterial activities of OPS-2071 against Clostridioides difficile were evaluated in comparison to...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Oka, Daisuke, Yamaya, Naomitsu, Kuno, Takuya, Asakawa, Yuta, Shiragiku, Toshiyuki, Chen, Liang, Xue, Jingbo, Mamuti, Abudusaimi, Ye, Fangguo, Sun, Jiangqin, Ohguro, Kinue, Miyamoto, Hisashi, Uematsu, Yukitaka, Inagaki, Katsuya, Cheng, Jie-Fei, Matsumoto, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097418/
https://ncbi.nlm.nih.gov/pubmed/33495229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01170-20
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