In Vitro and In Vivo Antibacterial Activities of a Novel Quinolone Compound, OPS-2071, against Clostridioides difficile

OPS-2071 is a novel quinolone antibacterial agent characterized by low oral absorption that reduces the risk of adverse events typical of fluoroquinolone class antibiotics. The in vitro and in vivo antibacterial activities of OPS-2071 against Clostridioides difficile were evaluated in comparison to...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Oka, Daisuke, Yamaya, Naomitsu, Kuno, Takuya, Asakawa, Yuta, Shiragiku, Toshiyuki, Chen, Liang, Xue, Jingbo, Mamuti, Abudusaimi, Ye, Fangguo, Sun, Jiangqin, Ohguro, Kinue, Miyamoto, Hisashi, Uematsu, Yukitaka, Inagaki, Katsuya, Cheng, Jie-Fei, Matsumoto, Makoto
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097418/
https://ncbi.nlm.nih.gov/pubmed/33495229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01170-20
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