In Vitro and In Vivo Antibacterial Activities of a Novel Quinolone Compound, OPS-2071, against Clostridioides difficile

OPS-2071 is a novel quinolone antibacterial agent characterized by low oral absorption that reduces the risk of adverse events typical of fluoroquinolone class antibiotics. The in vitro and in vivo antibacterial activities of OPS-2071 against Clostridioides difficile were evaluated in comparison to...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Oka, Daisuke, Yamaya, Naomitsu, Kuno, Takuya, Asakawa, Yuta, Shiragiku, Toshiyuki, Chen, Liang, Xue, Jingbo, Mamuti, Abudusaimi, Ye, Fangguo, Sun, Jiangqin, Ohguro, Kinue, Miyamoto, Hisashi, Uematsu, Yukitaka, Inagaki, Katsuya, Cheng, Jie-Fei, Matsumoto, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097418/
https://ncbi.nlm.nih.gov/pubmed/33495229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01170-20
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