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Toll‐like receptor 4 is activated by platinum and contributes to cisplatin‐induced ototoxicity

Toll‐like receptor 4 (TLR4) recognizes bacterial lipopolysaccharide (LPS) and can also be activated by some Group 9/10 transition metals, which is believed to mediate immune hypersensitivity reactions. In this work, we test whether TLR4 can be activated by the Group 10 metal platinum and the platinu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO Rep
Hauptverfasser: Babolmorad, Ghazal, Latif, Asna, Domingo, Ivan K, Pollock, Niall M, Delyea, Cole, Rieger, Aja M, Allison, W Ted, Bhavsar, Amit P
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097357/
https://ncbi.nlm.nih.gov/pubmed/33733573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051280
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