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Toll‐like receptor 4 is activated by platinum and contributes to cisplatin‐induced ototoxicity

Toll‐like receptor 4 (TLR4) recognizes bacterial lipopolysaccharide (LPS) and can also be activated by some Group 9/10 transition metals, which is believed to mediate immune hypersensitivity reactions. In this work, we test whether TLR4 can be activated by the Group 10 metal platinum and the platinu...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Babolmorad, Ghazal, Latif, Asna, Domingo, Ivan K, Pollock, Niall M, Delyea, Cole, Rieger, Aja M, Allison, W Ted, Bhavsar, Amit P
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097357/
https://ncbi.nlm.nih.gov/pubmed/33733573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051280
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