Necroptosis and Apoptosis Contribute to Cisplatin and Aminoglycoside Ototoxicity

Ototoxic side effects of cisplatin and aminoglycosides have been extensively studied, but no therapy is available to date. Sensory hair cells, upon exposure to cisplatin or aminoglycosides, undergo apoptotic and necrotic cell death. Blocking these cell death pathways has therapeutic potential in the...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ruhl, Douglas, Du, Ting-Ting, Wagner, Elizabeth L., Choi, Jeong Hwan, Li, Sihan, Reed, Robert, Kim, Kitae, Freeman, Michael, Hashisaki, George, Lukens, John R., Shin, Jung-Bum
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462451/
https://ncbi.nlm.nih.gov/pubmed/30733218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1384-18.2019
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