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ORC-13661 protects sensory hair cells from aminoglycoside and cisplatin ototoxicity
Aminoglycoside (AG) antibiotics are widely used to prevent life-threatening infections, and cisplatin is used in the treatment of various cancers, but both are ototoxic and result in loss of sensory hair cells from the inner ear. ORC-13661 is a new drug that was derived from PROTO-1, a compound firs...
Shranjeno v:
| izdano v: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6693895/ https://ncbi.nlm.nih.gov/pubmed/31391343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126764 |
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