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Moderate DNA hypomethylation suppresses intestinal tumorigenesis by promoting caspase-3 expression and apoptosis

Global DNA hypomethylation is a most common epigenetic alteration in human neoplasia. However, accumulative evidence shows that global DNA hypomethylation impacts tumorigenesis in a tissue-specific manner, promoting tumorigenesis in some but suppressing tumorigenesis in others including colorectal c...

詳細記述

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書誌詳細
出版年:Oncogenesis
主要な著者: Duan, Xiaoya, Huang, Yuanyong, Chen, Xiaoxing, Wang, Wencai, Chen, Jiwei, Li, Jialun, Yang, Wei, Li, Jiwen, Wu, Qihan, Wong, Jiemin
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096944/
https://ncbi.nlm.nih.gov/pubmed/33947834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-021-00328-9
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