N6-methyladenosine demethylase FTO impairs hepatic ischemia–reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation

Despite N6-methyladenosine (m6A) is functionally important in various biological processes, its role and the underlying regulatory mechanism in the liver remain largely unexplored. In the present study, we showed that fat mass and obesity-associated protein (FTO, an m6A demethylase) was involved in...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Du, Ying Dong, Guo, Wen Yuan, Han, Cong Hui, Wang, Ying, Chen, Xiao Song, Li, Da Wei, Liu, Jin Long, Zhang, Ming, Zhu, Nan, Wang, Xin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096847/
https://ncbi.nlm.nih.gov/pubmed/33947842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03622-x
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