N6-methyladenosine demethylase FTO impairs hepatic ischemia–reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation

Despite N6-methyladenosine (m6A) is functionally important in various biological processes, its role and the underlying regulatory mechanism in the liver remain largely unexplored. In the present study, we showed that fat mass and obesity-associated protein (FTO, an m6A demethylase) was involved in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Du, Ying Dong, Guo, Wen Yuan, Han, Cong Hui, Wang, Ying, Chen, Xiao Song, Li, Da Wei, Liu, Jin Long, Zhang, Ming, Zhu, Nan, Wang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096847/
https://ncbi.nlm.nih.gov/pubmed/33947842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03622-x
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