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Thermoresponsive Hydrogel-based Local Delivery of Simvastatin for the Treatment of Periodontitis

Except for routine scaling and root planing, there are few effective nonsurgical therapeutic interventions for periodontitis and associated alveolar bone loss. Simvastatin (SIM), one of the 3-hydroxy-3-methylglutaryl-cosenzyme A reductase inhibitors, which is known for its capacity as a lipid-loweri...

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Bibliografski detalji
Izdano u:Mol Pharm
Glavni autori: Chen, Ningrong, Ren, Rongguo, Wei, Xin, Mukundan, Roshni, Li, Guojuan, Xu, Xiaoke, Zhao, Gang, Zhao, Zhifeng, Lele, Subodh M., Reinhardt, Richard A., Wang, Dong
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096715/
https://ncbi.nlm.nih.gov/pubmed/33754729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c01196
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