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Thermoresponsive Hydrogel-based Local Delivery of Simvastatin for the Treatment of Periodontitis

Except for routine scaling and root planing, there are few effective nonsurgical therapeutic interventions for periodontitis and associated alveolar bone loss. Simvastatin (SIM), one of the 3-hydroxy-3-methylglutaryl-cosenzyme A reductase inhibitors, which is known for its capacity as a lipid-loweri...

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Publicado en:Mol Pharm
Autores principales: Chen, Ningrong, Ren, Rongguo, Wei, Xin, Mukundan, Roshni, Li, Guojuan, Xu, Xiaoke, Zhao, Gang, Zhao, Zhifeng, Lele, Subodh M., Reinhardt, Richard A., Wang, Dong
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096715/
https://ncbi.nlm.nih.gov/pubmed/33754729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c01196
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