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Local Application of Pyrophosphorylated Simvastatin Prevents Experimental Periodontitis
PURPOSE. Simvastatin (SIM), a HMG-CoA reductase inhibitor widely prescribed for hypercholesterolemia, has been reported to ameliorate inflammation and promote osteogenesis. Its clinical applications on these potential secondary indications, however, have been hampered by its lack of osteotropicity a...
Shranjeno v:
| izdano v: | Pharm Res |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7424626/ https://ncbi.nlm.nih.gov/pubmed/29943090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2444-z |
| Oznake: |
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