Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi(‡)

Telomerase plays critical roles in cellular aging, in the emergence and/or development of cancer, and in the capacity for stem-cell renewal, consists of a catalytic telomerase reverse transcriptase (TERT) and a template-encoding RNA (TER). TERs from diverse organisms contain two conserved structural...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Zhai, Liu-Tao, Rety, Stephane, Chen, Wei-Fei, Song, Ze-Yu, Auguin, Daniel, Sun, Bo, Dou, Shuo-Xing, Xi, Xu-Guang
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096264/
https://ncbi.nlm.nih.gov/pubmed/33856462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab261
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