SIRT3 consolidates heterochromatin and counteracts senescence

Sirtuin 3 (SIRT3) is an NAD(+)-dependent deacetylase linked to a broad range of physiological and pathological processes, including aging and aging-related diseases. However, the role of SIRT3 in regulating human stem cell homeostasis remains unclear. Here we found that SIRT3 expression was downregu...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Diao, Zhiqing, Ji, Qianzhao, Wu, Zeming, Zhang, Weiqi, Cai, Yusheng, Wang, Zehua, Hu, Jianli, Liu, Zunpeng, Wang, Qiaoran, Bi, Shijia, Huang, Daoyuan, Ji, Zhejun, Liu, Guang-Hui, Wang, Si, Song, Moshi, Qu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
NAR Breakthrough Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096253/
https://ncbi.nlm.nih.gov/pubmed/33706382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab161
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